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PLoS ONE 10 , e0123454

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a high-cardiovascular-risk kidney cohort showed a slower decline in kidney function and about a third less protein leak, which travels to a similar-risk body, not a healthy one. Lean and metabolically healthy: a safety read, not an efficacy target No long trial has tested tirzepatide in lean, metabolically healthy people

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We found that temporal degradation of different V-ATPase subunits recapitulated the autophagy-activating effect of the Vma2-AID*-9MYC protein